Obstructive sleep apnea has been implicated in deleterious effects on cancer incidence and outcomes. Among the cancers identified as affected by sleep apnea, melanoma has consistently emerged as particularly susceptible. Furthermore, evidence suggests that exosomes, microparticles that originate from all cells and contain a variety of biologically active molecules such as microRNAs, can modify cancer cell properties. Here, we examined whether exosomes from sleep apnea patients can alter melanoma cell properties, and whether such effects were attributable to selected microRNA candidates, and affected melanoma cells harboring different mutations differently.
El síndrome de apneas del sueño, caracterizado por la repetición de episodios de interrupción parcial o completa del flujo a través de las vías aéreas…
The aim of the present study was to examine the relationships between the responses to progressive isocapnic hypoxia and hypoxic withdrawal test in patients with…
